Ultrashort echo-time MRI as a substitute to CT for skull aberration correction in transcranial focused ultrasound: in vitro comparison on human calvaria
نویسندگان
چکیده
Background/introduction Clinical transcranial MR-guided focused ultrasound (TcMRgFUS) brain treatment systems compensate for skull-induced beam aberrations by adjusting the phase and amplitude of individual ultrasound transducer elements. These corrections are currently calculated based on a pre-acquired CT scan of the patient’s head. The purpose of the work presented here is to demonstrate the feasibility of using ultrashort echo-time (UTE) MRI instead of CT to calculate and apply aberration corrections on a clinical TcMRgFUS system.
منابع مشابه
T1-weighted MRI as a substitute to CT for skull aberration correction in transcranial focused ultrasound: in vivo feasibility and in vitro comparison on human calvaria
Background/introduction CT scans have been used to refocus ultrasound for clinical transcranial MRI-guided focused ultrasound (TcMRgFUS). The refocusing of the ultrasound arrays is a crucial step in TcMRgFUS therapy because skulls distort sound beams due to the ununiformed shape and composition of the bone. CT scan based algorithms have been developed to estimate the phase shifts induced by the...
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BACKGROUND Non-invasive high-intensity focused ultrasound (HIFU) can be used to treat a variety of disorders, including those in the brain. However, the differences in acoustic properties between the skull and the surrounding soft tissue cause aberrations in the path of the ultrasonic beam, hindering or preventing treatment. METHODS We present a method for correcting these aberrations that is...
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عنوان ژورنال:
دوره 3 شماره
صفحات -
تاریخ انتشار 2015